Cryoprecipitate
- A frozen blood product prepared from plasma
- Each 15 mL unit typically contains 100 IU of factor VIII, 250 mg of fibrinogen, as well as von Willebrand factor (vWF) and factor XIII.
- Used commonly for DIC to keep fibrinogen levels > 1.0.
- 1 unit of cryo per 5kg patient weight will increase fibrinogen by about 100 mg/dL. Therefore number of bags = 0.2 x weight (kg) to provide about 100mg/dL fibrinogen.
- Many institutions use a standard dose of 10 units and then repeat if needed.
References
- http://en.wikipedia.org/wiki/Cryoprecipitate
- http://reference.medscape.com/drug/cryo-cryoprecipitate-999498
- http://www.transfusion.com.au/sites/default/files/iTRANSFUSE%202.2%20CRYO.pdf
- http://www.perthhaematology.com.au/cryo.ht
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